Cord Blood Research & Clinical Trials
In the late 1980s, doctors began treating blood cancers and leukemia with cord blood stem cells. Up until then, patients could only utilize bone marrow stem cells. There were many cases that bone marrow treatment failed, or a bone marrow match could not be found. Researchers continue to explore new applications for the use of cord blood stem cells every day around the world. Today, over 80 diseases have been treated with cord blood units! The FDA regularly reviews the results of clinical trials for new treatments.
Researchers continue to conduct cutting-edge clinical trials in areas such as:
- Early hearing loss in infants
- Cerebral Palsy
- Cleft Pallets
- Congenital Pediatric Disorders
Bringing opportunity to CNY!
At Upstate Cord Blood Bank we offer families the option to donate the cord blood to research if it is not clinically useful. Therefore, the stem cells will not go to waste as they are invaluable to improving medical research. This is especially beneficial for studies seeking to advance new treatments for cancer and chronic diseases. This makes the Upstate Cord Blood Bank in Syracuse, New York a valuable resource for physicians, researchers, and businesses across the US.
The Bank operates under strict guidelines and protocols established by state and federal health organizations for quality assurance. This includes NYSDOH, FDA, FACT, AABB, CLIA, and CAP. Regular inspections and testing are done to ensure that our facility remains a safe haven for banked cord blood. Above all, this makes it possible to work with the regional hospitals and providers to enable mothers in the Central New York area the opportunity to donate their cord blood to the public bank.
Cord blood is only one of three sources of blood-forming cells used in transplants. These cells, known as hematopoietic stem cells (HSCs), are also found in bone marrow and peripheral blood stem cells.
HSCs are capable of renewing themselves into a variety of different cell types based on the treatment needs of the patient receiving the transplant. Because the healthy HSCs are extracted from cord blood at an early development stage, this gives the cells an even greater ability to self-replicate, and they are less likely to be rejected by the patient’s immune system.
When your cord blood arrives at our facility, we will run tests and begin processing the cord blood for long-term storage. During our process, we use highly specialized equipment to extract the HSCs from your baby’s cord blood. The HSCs are secured in a vacuum-sealed overwrap bag made of TeflonTM and then put into a protective metal receptacle to be stored in our state-of-the-art cryogenic tanks.
Each cord blood unit (CBU) is recorded in our local database using a unique identification number that keeps your identity anonymous, but makes the unit easily retrievable when needed for lifesaving treatment. However, when you donate specifically to the public bank, the CBU data will also be uploaded to an international registry database to be made available for patients all over the world.
Cord blood is being used for both children and adult patients. However, cord blood is used more often in children for transplants. This is due to the fact that each CBU has a limited number of HSCs. Smaller patients will usually receive enough HSCs from one CBU, but fully grown patients will sometimes need to receive two or more combined CBUs for treatment.
When patients are in need of a lifesaving stem cell transplant, there are several reasons why a doctor might choose cord blood:
- Cord blood does not have to be as closely matched to a patient as a marrow donor. This is a good option for patients with uncommon tissue types.
- Cord blood units are quickly available for transplantation as they are in storage and ready for use.
- Studies have found that graft-versus-host-disease (GVHD) is less common and less severe after a cord blood transplant than after a transplant using peripheral blood stem cells.
Cord blood and stem cells are in high demand, not only for immediate use as a transplantable option for treatment of many diseases, but for continued advancement of research that is essential for the future of lifesaving treatments. If you would like to partner with us to advance cord blood research, please call Upstate Cord Blood Bank at (315) 492-2600 today.